Super Quad-Mix

Phentolamine is classified as an Alpha-Adrenoceptor Antagonists. Noradrenaline affects the smooth muscle tone of the penile tissues by keeping the corpora cavernosa in a contracted state. By blocking the functional noradrenaline receptors, the Alpha-Adrenoceptor, erectile response can be achieved. Phentolamine competes with endogenous norepinephrine for the Alpha1-Adrenoceptor and Alpha2-Adrenoceptor. Phentolamine has similar binding capacities to both receptors.


QuadMix is administered as a penile self-injection, typically considered to be the most powerful class of anti-erectile dysfunction agents. While the components of QuadMix (Papaverine, Phentolamine, Prostaglandin E1, Atropine) are, on their own, indicated for a vast number of different conditions, the practice of bringing them together in concert to treat erectile dysfunction has become commonplace in sexual medicine and is now considered the go-to treatment if a patient is not responsive to conventional PDE5 inhibitors such as Viagra or Cialis.QuadMix is used in the treatment of erectile dysfunction in males. QuadMix contains four drugs from complimentary classes designed to act synergistically, mixed into a sterile injection.


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